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. 2023 Mar 23;24(7):6060. doi: 10.3390/ijms24076060

Figure 4.

Figure 4

Effect of CB2, PPARα and PPARγ receptors antagonists on triglyceride accumulation per cell. Cells were incubated with different concentrations of BCP and 0.5 mM FFAm, in the presence or absence of specific receptor antagonists for 24 h. (A) Treatment of HepG2 cells with 5 µM CB2 antagonist AM630. (B) Treatment with 100 nM PPARα antagonist GW6471. (C) Treatment with 10 µM PPARγ antagonist GW9662. Data are expressed as a percentage change with respect to 0.5 mM FFA control condition (set equal to 100) and represent the mean ± SEM of five independent experiments. ** p < 0.01; *** p < 0.001 vs. BCP + 0.5 mM FFAm treated cells.