Figure 10.

The evolutionary profile of genes belonging to GO Biological Processes: (A) ‘cellular response to stress’ (GO:0033554); (B) ‘mitotic cell cycle’ (GO:0000278). Red dotted lines show confidence intervals for individual phylostrata (p = 0.05). For all phylostrata taken as points, Spearman rank correlation between gene proportion and phylostrata: r = −0.96, p < 0.0001 (A); r = −0.82, p < 0.001 (B). Phylostrata: 1—cellular organisms (Prokaryota); 2—Eukaryota; 3—Opisthokonta; 4—Metazoa; 5—Eumetazoa; 6—Bilateria; 7—Chordata; 8—Vertebrata; 9—Euteleostomi; 10—Tetrapoda; 11—Amniota; 12—Mammalia; 13—Theria; 14—Eutheria; 15—Boreoeutheria; 16—Primates; 17—Hominidae. The pictures at the top show recent organisms corresponding to phyletic branching used for human gene dating.