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. 2023 Mar 23;24(7):6089. doi: 10.3390/ijms24076089

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Mass spectrometry analysis of neurotransmitters and their metabolites in the cerebellum. (A) Heatmap of neurotransmitter expression in each group. (B) Relative expressions of glutamate and GABA. (C) Relative expressions of phenylalanine, tyrosine, dopamine, 3,4-dihydroxyphenylacetic acid (DOPAC), homovanillic acid (HVA), norepinephrine, and ratios of DOPAC/dopamine, HVA/dopamine, and dopamine/tyrosine. (D) Relative expressions of tryptophan, serotonin, 5-hydroxyindole-3-acetic acid (5-HITT), and ratios of serotonin/tryptophan and 5-HIAA/serotonin. Indicators: * p-values ≤ 0.05, ◯ Non-3-AP SAL group, ☐ 3-AP SAL group, △ 3-AP H.E. group.