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. 2023 Mar 25;24(7):6234. doi: 10.3390/ijms24076234

Figure 4.

Figure 4

Expression of HIF-1α and related genes in monocytes from HV and septic patients. (A) Basal expressions of HIF1A, VEGFA, IRAKM, and PDL1 in monocytes from HV (n = 7) and septic patients (n = 7) by RT-qPCR are shown. *, p < 0.05; ** p < 0.01 in Mann–Whitney t test. (B–D) Monocytes from HV and septic patients were stimulated with 10 ng/mL of LPS for 16 h in combination or not with 3 µg/mL of TASE. Relative expressions of VEGFA (B), IRAKM (C), and PDL1 (D) are shown. *, p < 0.05 in paired t test. Bars represent mean ± SD.