Figure 1.

Higher mortality rate in male wild-type (WT) and cardiomyocyte-specific MAO-B knockout (KO) mice compared to female mice. WT and KO hearts were exposed to 45 min ischemia and 120 min reperfusion. Summary of the number of operated mice before and after surgery. Excluded mice had blood in the urine or surgery complications. There is no significant difference among groups when analyzed groups separately by Chi-square test or between WT and KO animals when analyzed by Fisher’s exact test. However, there is a slightly decreasing tendency but not significant in all-cause mortality in female individuals as compared to males when analyzed by Fisher’s exact test (* p = 0.103).