Table 1.
The 10 most highly expressed alternatively polyadenylated genes in articular chondrocytes regardless of disease state.
| Gene Name, (Gene Symbol), Ensembl Gene ID | Gene Locus (Strand) | Sites (Proximal to Distal) | Site Distance from Proximal Site (bp) | Site Mean Read Count ± SD |
|---|---|---|---|---|
| Decorin, (DCN), ENSG00000011465 | chr12:91140483–91182823 (antisense) | 91145968 | 0 | 12,270 ± 8494 |
| 91145870 | 98 | 19,760 ± 13,585 | ||
| 91145526 | 442 | 51,032 ± 39,570 | ||
| Noncoding nuclear-enriched abundant transcript 2, (MALAT1), ENSG00000251562 | chr11:65497687–65506515 (sense) | 65499339 | 0 | 28,517 ± 21,758 |
| 65499659 | 320 | 21,804 ± 17,950 | ||
| 65499698 | 359 | 100,707 ± 98,832 | ||
| 65499736 | 397 | 99,063 ± 96,843 | ||
| 65499776 | 437 | 50,554 ± 37,148 | ||
| 65499794 | 455 | 5531 ± 4083 | ||
| 65500522 | 1183 | 6120 ± 6761 | ||
| 65500558 | 1219 | 5446 ± 5383 | ||
| Complement factor H, (CFH), ENSG00000000971 | chr11:65497687–65506515 (sense) | 196701562 | 0 | 38,800 ± 68,040 |
| 196747501 | 45,939 | 8984 ± 9034 | ||
| Clusterin, (CLU), ENSG00000120885 | chr8:27596916–27614699 (antisense) | 27609020 | 0 | 2143 ± 1472 |
| 27608995 | 25 | 6215 ± 3978 | ||
| 27608957 | 63 | 7438 ± 4695 | ||
| 27597996 | 11,024 | 33,471 ± 22,377 | ||
| 27597813 | 11,207 | 8339 ± 9719 | ||
| 27597728 | 11,292 | 21,976 ± 21,562 | ||
| Osteonectin, (SPARC), ENSG00000113140 | chr5:151661095–151686974 (antisense) | 151662435 | 0 | 22,006 ± 29,354 |
| 151661449 | 986 | 4341 ± 5672 | ||
| 60S ribosomal protein L7a, (RPL7A), ENSG00000280858 | chr9:133348217–133351425 (Sense) | 133351412 | 0 | 4060 ± 2684 |
| 133351424 | 12 | 18,479 ± 12,447 | ||
| Prolargin, (PRELP), ENSG00000188783 | chr1:203475805–203491351 (sense) | 203487161 | 0 | 17,465 ± 13,603 |
| 203489613 | 2452 | 16,419 ± 13,500 | ||
| Cartilage intermediate layer protein, (CILP), ENSG00000138615 | chr15:65194759–65211472 (antisense) | 65196529 | 0 | 3135 ± 4161 |
| 65196251 | 278 | 13,156 ± 16,572 | ||
| 65196000 | 529 | 4965 ± 5868 | ||
| H3 histone family member 3B, (H3F3B), ENSG00000132475 | chr17:75776433–75785892 (antisense) | 75778250 | 0 | 2376 ± 2438 |
| 75778023 | 227 | 2255 ± 2841 | ||
| 75777456 | 794 | 12,733 ± 12,977 | ||
| Early growth response 1, (EGR1), ENSG00000120738 | chr5:138465478–138469302 (sense) | 138469224 | 0 | 2641 ±2780 |
| 138469240 | 16 | 729 ± 649 | ||
| 138469301 | 77 | 12,484 ± 16,106 |