Figure 4.

Effect of gold nanoparticles on siRNA’s secondary structure (θ—ellipticity). (A) Spectra CD of siRNA at the presence of AuNP14a, and (B) AuNP14b. (C) Changes in mean ellipticity at λ = 265 nm. Measurements were conducted in λ = 200–320 nm in phosphate buffer, pH = 7.4. The concentration of siRNA 1 µmol/L. The values are the mean ± standard error of the mean (SEM), n = 3.