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. 2023 Apr 6;24(7):6816. doi: 10.3390/ijms24076816

Figure 1.

Figure 1

KPT-330 combined with AZA synergistically inhibited AML cell growth. (A) Cell proliferation assay result (dose-dependent curve) for KPT-330 in U937 and MV4-11 for 72 h. (B) Cell proliferation assay result (dose-dependent curve) for AZA in U937 and MV4-11 for 72 h. (C) Synergistic effect of KPT-330 with various doses of AZA on cell proliferation arrest and CalcuSyn analysis in U937 cells. (D) Synergistic effect of KPT-330 with various doses of AZA on cell proliferation arrest and CalcuSyn analysis in MV4-11 cells. (E) Synergistic effect of KPT-330 with various doses of AZA on cell proliferation arrest and CalcuSyn analysis in THP-1 cells. “……” indicates IC50, “----” indicates the range of synergies. ** p < 0.01, *** p < 0.001.