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. 2023 Apr 6;24(7):6816. doi: 10.3390/ijms24076816

Figure 5.

Figure 5

XPO1/eIF4E was highly expressed and correlated in AML patients. (A) Gene expression of XPO1 and eIF4E in AML patients (n = 194) and healthy donors (n = 20) extracted from the GEO (GSE11486) database. (B) Gene expression of XPO1 and eIF4E in AML patients (n = 542) and healthy donors (n = 74) from the GEO (GSE13159) database. (C) Expression of the XPO1 and eIF4E genes in AML patients (n = 202) and healthy donors (n = 69) from the GEO (GSE15061) database. (D) In our institute’s cohort research, blood samples from AML patients (n = 53) express greater levels of XPO1 and eIF4E than samples from healthy donors (n = 53). (E−G) the association between XPO1 and eIF4E in the TCGA dataset and the dataset from our institute. * p < 0.05, ** p < 0.01, *** p < 0.001, ns: p > 0.05.