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. 2023 Apr 6;24(7):6816. doi: 10.3390/ijms24076816

Figure 7.

Figure 7

Synergistic effect of KPT-330 with AZA on cell growth arrest in primary cells from the AML patients. Effect of drug treatment (DMSO, KPT-330, AZA, and combo) on the cell growth arrest and CalcuSyn analysis in primary cells from AML patient 1 (PT1, (A)). Effect of drug treatment (DMSO, KPT-330, AZA, and combo) on the cell growth arrest and CalcuSyn analysis in primary cells from AML patient 2 (PT2, (B)). Bliss analysis for the synergistic effect in PT1 (C) and PT2 (D) using the SynergyFinder Web application. Synergy score: <−10, antagonistic; from −10 to 10, additive; >10, synergistic. *** p < 0.001.