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LEfSe analysis for high-dimensional biomarker discovery and explanation, based on linear discriminant analysis (LDA) effect size (LEfSe), employed to identify ASV features that resulted in statistical differences among T0 and T1 gut microbiota groups. Histogram represents the LDA scores until the taxonomy level genus (L6) filtered by statistical significance between the two groups. In red are represented microbial biomarkers for the patients at T1.
