Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Mar 31;24(7):6577. doi: 10.3390/ijms24076577

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Top 10 enriched compounds that can be used as repurposing drugs against the top 250 co-upregulated genes in RCC according to DrugMatrix (a) and cMap (b,c) databases. The repurposed drugs upregulating or downregulating the co-upregulated genes in RCC, according to Old cMAP analysis are depicted in (b,c), respectively. Asterisks (*) indicate the terms with significant adjusted p-values (<0.05). The scatterplots (right) were created using UMAP and depict clusters of similar compounds. The significantly enriched terms of the associated gene sets are denoted.