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. 2023 Apr 4;24(7):6707. doi: 10.3390/ijms24076707

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Resveratrol attenuates skin mast cell activation and reactivity without affecting mast cell numbers: (a) Mean total mast cell numbers, (b) activation (degranulation), and (c) FcεRIα mRNA expression levels after 7 days of epicutaneous exposure to saline (S) and vehicle for resveratrol (V) (dark grey filled bars), ovalbumin (O) and V (black filled bars), S with resveratrol (R) (empty bars), or O with R (light grey bars). N = 3–9 mice per experimental group and 15 images per mouse (a,b), n.s., not significant.