Table 2.
Univariate and Multivariate Analysis of Factors Associated with Overall Survival (n=448).
| Characteristics | Total (N) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
| Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | ||
| Sex | 448 | ||||
| female | 185 | Reference | |||
| male | 263 | 1.128 (0.785-1.620) | 0.516 | ||
| Age | 448 | ||||
| <60 | 234 | Reference | |||
| ≥60 | 214 | 0.948 (0.665-1.352) | 0.769 | ||
| BMI | 448 | ||||
| <25 | 332 | Reference | |||
| ≥25 | 116 | 1.028 (0.684-1.545) | 0.893 | ||
| Stage | 448 | ||||
| I+II | 260 | Reference | |||
| III+IV | 188 | 5.020 (3.353-7.516) | <0.001 | 3.904 (2.513-6.062) | <0.001 |
| Grade | 448 | ||||
| G1+G2 | 418 | Reference | |||
| G3+M | 30 | 2.753 (1.599-4.739) | <0.001 | 1.951 (1.120-3.399) | 0.018 |
| Size | 448 | ||||
| <5 | 250 | Reference | |||
| ≥5 | 198 | 1.102 (0.773-1.572) | 0.591 | ||
| Site | 448 | ||||
| Colon | 241 | Reference | |||
| Rectum | 207 | 0.834 (0.582-1.194) | 0.321 | ||
| NVI | 448 | ||||
| No | 273 | Reference | |||
| Yes | 175 | 3.021 (2.099-4.349) | <0.001 | 1.999 (1.367-2.923) | <0.001 |
| Chemotherapy | 448 | ||||
| No | 224 | Reference | |||
| Yes | 224 | 1.715 (1.188-2.476) | 0.004 | 0.945 (0.645-1.383) | 0.770 |
BMI, body mass index; M, Mucinous adenocarcinoma; NVI, nerve or vascular invasion.