Table 3.
Univariate and Multivariate Analysis of Factors Associated with Overall Survival (n=448).
| Characteristics | Total (N) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
| Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | ||
| CEA | 448 | ||||
| <6.5 | 320 | Reference | |||
| ≥6.5 | 128 | 1.629 (1.132-2.344) | 0.009 | 1.020 (0.688-1.512) | 0.922 |
| CA19-9 | 448 | ||||
| <27 | 353 | Reference | |||
| ≥27 | 95 | 1.904 (1.302-2.784) | <0.001 | 1.200 (0.794-1.814) | 0.387 |
| NLR | 448 | ||||
| NLR<2.81 | 335 | Reference | |||
| NLR≥2.81 | 113 | 2.140 (1.488-3.078) | <0.001 | 1.664 (1.105-2.508) | 0.015 |
| PLR | 448 | ||||
| PLR<168.24 | 247 | Reference | |||
| PLR≥168.24 | 201 | 1.820 (1.271-2.605) | 0.001 | 1.111 (0.740-1.666) | 0.612 |
| LMR | 448 | ||||
| LMR<5.46 | 347 | Reference | |||
| LMR>5.46 | 101 | 0.341 (0.188-0.618) | <0.001 | 0.478 (0.255-0.898) | 0.022 |
CEA, carcinoembryonic antigen; CA19-9, carbohydrate antigen 19–9; NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio; LMR, lymphocyte-to-monocyte ratio.