Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Apr 6;24(7):6865. doi: 10.3390/ijms24076865

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Differential expression of circRNAs between CTRL and HFD SPZ. (A) The distribution of up- and downregulated DE-circRNAs, among a total of 109 DE-circRNAs, in HFD compared with CTRL SPZ. (B) Hierarchical clustering analysis of DE-circRNAs in CTRL SPZ (samples CTRL-1, CTRL-2, CTRL-3) and HFD SPZ (samples HFD-1, HFD-2, HFD-3); the expression values (fold change > 1.5, p < 0.05) were represented in different colors, indicating expression levels above and below the median expression level across all samples. (C) The volcano plot was constructed using fold change and p-values; in detail, the values on X and Y axes are log2 (FC = fold change) and –log10 (p-values), respectively. Red points in the volcano plot represent the DE-circRNAs with statistical significance. (D) The distribution of up- and downregulated DE-circRNAs in the mouse genome, according to their host gene location.