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Effects of CBDA and THCA on hippocampal BDNF/CREB signaling-related protein levels in Aβ1–42-treated mice. (A) Representative Western blots of BDNF, p-CREB, and p-TrkB proteins. (B–D) Western blot densitometry results for (B) BDNF, (C) p-TrkB/TrkB, and (D) p-CREB/CREB. (mean ± SEM, # p < 0.05, ## p < 0.005, and ### p < 0.001 vs. PBS-treated, * p < 0.05, ** p < 0.005, and *** p < 0.001 vs. Aβ1–42-treated, one-way ANOVA followed by Fisher’s LSD; n = 5 per group).
