Figure 4.

Cell proliferation changes in HEK293 (a) and HepG2 (b) cells upon H₂O₂ treatment and the addition of the substances. The blue color shows DAPI-stained cell nuclei; the green represents Ki67 antibody staining. (a) Cell proliferation was decreased due to H₂O₂ induction, which was reversed by treatment with UPla, Ulu, and the positive control lipoic acid in HEK293 cells; (b) UPla, Ulu, as well as transferrin reversed the cell proliferation decline in HepG2 cells. The results are representative of three independent experiments.