Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Piezo1 channel. Structure and regulation of the channel. Piezo1 protein has a homotrimeric architecture with three propeller-shaped blades. The pore consists of the extracellular Cap structure, three pairs of the outer and inner helices (TM domains), and the intracellular C-terminal domain (CTD). The peripheral mechanotransduction region contains the beam structure, the peripheral blade, and the anchor domain (the figure was created using biorender.com).
