Table 1.
Physical and chemical characteristics of human plasma lipoproteins.
| Plasmatic Lipoprotein |
Density (g/mL) |
Source | Composition (%) | Apolipoproteins | ||
|---|---|---|---|---|---|---|
| Lipid | Protein | Major | Others | |||
| Chylomicrons | <0.95 | intestine | 98–99 | 1–2 | ApoB-48 | ApoA-I, A-II, A-IV, A-V |
| VLDL | 0.95–1.006 | liver | 90–93 | 6–8 | ApoB-100 | ApoA-I, C-II, C-III, E, A-V |
| IDL | 1.006–1.019 | catabolism of VLDL | 89 | 11 | ApoB-100 | ApoC-II, C-III, E |
| LDL | 1.019–1.063 | catabolism of VLDL via IDL | 79 | 21 | ApoB-100 | - |
| HDL | 1.063–1.210 | liver, intestine, catabolism of CM and VLDL | 67 | 33 | ApoA-I | ApoA-II, C-III, E, M |
| Lp(a) | 1.006–1.125 | liver | 80 | 20 | Apo(a) | ApoB-100 |
The physical and chemical overall characteristics of human plasma lipoproteins, adapted from the 2019 ESC/EAS Guidelines for the Management of Dyslipidaemias [1].