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. 2023 Apr 1;12(7):2642. doi: 10.3390/jcm12072642

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Enrichment analysis of differentially expressed genes in VS stratified by the presence or absence of tinnitus. (A) Functional enrichment analysis of differentially expressed genes by using DAVID revealed functional gene categories. (B) All genes ranked according to the magnitude of expression change (fold change) between VS patients with and without tinnitus were analyzed for the enrichment of functional gene categories by using GSEA. Five of the six top GSEAs were associated with inflammation. The green line indicates the enrichment score. Red indicates positive correlation and blue indicates negative correlation in the ranked ordered dataset.