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Crystal structure of HIV-1 RT in complex with the elaborated compound 27 (PDB ID 8FFX). Atomic model of 27 (magenta) bound to HIV-1 RT residues (blue) in the NNRTI-binding pocket. Pocket residues forming hydrophobic interactions shows as sticks. Polder mFo–DFc (OMIT) map density (green mesh, 3σ) of 27. Created using PyMOL and BioRender.com.
