Table 1. Key resources.

REAGENT or RESOURCE	SOURCE	IDENTIFIER
Bacterial and virus strains
Escherichia coli OP50	CGC	N/A
Escherichia coli OP50 (xu363)	[34]	N/A
Chemicals, peptides, and recombinant proteins
Coenzyme B12 (adenosyl cobalamin)	MilliporeSigma	Cat# C0884
N-methyl-N-(trimethylsilyl)trifluoroacetamide (MSTFA)	MilliporeSigma	Cat#M-132
Methoxyamine hydrochloride	MilliporeSigma	Cat# 226904
DL-3-hydroxybutyric acid sodium salt	MilliporeSigma	Cat# H6501
Propionic acid	MilliporeSigma	Cat#81910
Sodium propionate (D5, 98%)	Cambridge Isotope Laboratories	Cat#DLM-1601-1
L-Lysine monohydrochloride (13C6, 99%)	Cambridge Isotope Laboratories	Cat# CLM-2247-H
L-Lysine monohydrochloride	MilliporeSigma	Cat# L5626
Ethyl acetoacetate	MilliporeSigma	Cat# 00410
Ethyl 3-hydroxybutyrate	MilliporeSigma	Cat# E30603
Ethyl acetate	MilliporeSigma	Cat# 270989
Deposited data
Transcriptome dataset (Effect of mutated dhgd-1(tm6671) on C. elegans metabolism)	This study	https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE201645
Experimental models: Organisms/strains
Caenorhabditis elegans N2 (wild type)	CGC	N/A
Caenorhabditis elegans F54D5.12(tm6671)	[42]	N/A
Caenorhabditis elegans Pmyo-3::GFPmito; Pmyo-3::lacZ::GFP(nls)	CGC	PD4251
Caenorhabditis elegans emb-27(g48) II	Dr. J.E. Irazoqui	GG48
Caenorhabditis elegans acdh-1(ok1489) I	CGC	VC1011
Caenorhabditis elegans nhr-68(gk708) V	CGC	VC1527
Software and algorithms
R: A Language for Data Analysis and Graphics, version 4.1	http://www.r-project.org	N/A
WormFlux	http://wormflux.umassmed.edu/	N/A
Other
Single quadrupole GC/MS	Agilent Technologies	5977B GC/MSD

CGC, Caenorhabditis Genetics Center; GC-MS, gas chromatography–mass spectrometry.