Table 9. Performance comparison of BiComp encoding, against LZMA and SW encodings, for drug-target binding affinity prediction, for Davis and Kiba datasets, using feature ablation experiments.
| Experiments | Davis | Kiba | ||||||
|---|---|---|---|---|---|---|---|---|
| CI(std) | MSE | (std) | AUPR(std) | CI(std) | MSE | (std) | AUPR(std) | |
| Feature ablation SW | 0.869 (0.001) | 0.284 | 0.541 (0.014) | 0.623 (0.005) | 0.886 (0.001) | 0.168 | 0.713 (0.016) | 0.812 (0.004) |
| Feature ablation LZMA | 0.885 (0.001) | 0.279 | 0.597 (0.015) | 0.681 (0.003) | 0.877 (0.002) | 0.177 | 0.693 (0.014) | 0.803 (0.005) |
| BiComp-DTA | 0.904 (0.001) | 0.237 | 0.696 (0.012) | 0.753 (0.006) | 0.891(<0.001) | 0.167 | 0.757 (0.012) | 0.834 (0.003) |
Values of CI, MSE, and AUPR are provided for BiComp compared to those of LZMA and SW encodings for Davis and Kiba datasets.