TABLE 2.

Associations of 7 psychiatric traits with epilepsy in MR analyses (based on ILAE data)

Exposure	IVW method			Weighted median method			MR‐Egger regression
	OR	95% CI	p	OR	95% CI	p	OR	95% CI	p
ADHD*	1.09	1.01–1.17	.018	1.06	0.97–1.17	.180	1.21	0.90–1.63	.265
ASD	0.99	0.92–1.06	.691	0.99	0.92–1.07	.803	0.89	0.62–1.26	.514
MDD*	1.17	1.03–1.33	.018	1.22	1.05–1.42	.011	2.16	0.99–4.70	.066
BIP*	0.93	0.88–0.98	.009	0.93	0.87–1.01	.074	0.95	0.67–1.33	.760
SCZ	1.00	0.96–1.04	.903	1.00	0.96–1.04	.906	0.96	0.76–1.21	.721
Insomnia	0.74	0.54–1.01	.056	0.69	0.45–1.05	.085	1.13	0.18–6.99	.896
Anxiety disorder	8.34× 10−4	4.61×10−7 −1.51	.064	1.35× 10−2	3.41×10−6 −53.42	.308	2.66× 10	1.24×10−5 −5.67×10−5	.411

*Psychiatric traits that has significant p value (p < .05) in IVW method.

Abbreviations: CI: confidence interval; IVW: inverse‐variance weighted; OR: odds ratio.