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Fingolimod decreases the level of proinflammation cytokine in the spleen. The mRNA levels of TNF‐α, INF‐γ, IL‐1β, IL‐6, iNOS, and ICAM‐1 in spleens were analyzed by quantitative real‐time PCR (qRT‐PCR) (n = 5, *p ＜0.05 vs. the control group; **p ＜0.05 vs. the c‐EAN group).
