Skip to main content
. 2023 Mar 30;15(7):1702. doi: 10.3390/nu15071702

Figure 7.

Figure 7

The effect of repeated once-a-day administration of CBD (cannabidiol; 20 mg/kg, p.o.) or OIL (rapeseed oil) for 9 days on EtOH (ethanol; 3.0 g/kg/day, i.p.)- or H2O (water for injection)-induced mRNA expression of DRD1, DRD2, DRD4, DRD5 in PCOR, HIP, and STRIA. Mean ± SEM, n = 9. Legend: AVoRG—arithmetic mean of mRNA reference genes values (for details, see Section 2.7. RNA Isolation and mRNA Level Changes Evaluation); DRD1, DRD2, DRD4, DRD5—dopamine receptor type 1, 2, 4, and 5, respectively; PCOR—prefrontal cortex; HIP—hippocampus; STRIA—striatum; *—a statistically significant vs. OIL + H2O in the same receptor, p < 0.05, in PCOR, in HIP (***, p < 0.001) and STRIA; ##—a statistically significant vs. OIL + EtOH in the same receptor, p < 0.01 in HIP, in PCOR and STRIA (###, p < 0.001); $$$—a statistically significant vs. CBD + H2O in the same receptor, p < 0.001.