Figure 3.

Metabolic markers and systolic blood pressure. (A) Fasting blood glucose levels and (B) plasma insulin levels measured in the HFD, HFD + exercise and HFD + BCAA + exercise groups at baseline (chow) and after 3 and 6 months of treatment. (C) Systolic blood pressure was assessed in mice of all experimental groups at baseline and at three separate time points after group allocation (2, 4, 6 months). High-fat diet (HFD), branched-chain amino acids (BCAA). Data are presented as mean ± SEM. ** p < 0.01, *** p < 0.001, # 0.05 < p < 0.08 (trend); b: significant difference HFD vs. HFD + BCAA + exercise group, c: significant difference HFD + exercise vs. HFD + BCAA + exercise group.