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. Author manuscript; available in PMC: 2023 Jul 27.
Published in final edited form as: Ann Surg. 2023 Apr 6;277(5):e1106–e1115. doi: 10.1097/SLA.0000000000005370

Table 3.

Probability of completion lymph node dissection and adjuvant systemic therapy based on patient, disease, and treating center factorsa

Completion Lymph Node Dissection Adjuvant Systemic Therapy
Odds Ratio (95% Confidence Interval) P-Value Odds Ratio (95% Confidence Interval) P-Value
Primary site
 Head and neck 2.19 (1.26, 3.80) 0.006 1.04 (0.66, 1.61) 0.877
 Trunk 1.10 (0.73, 1.66) 0.657 1.06 (0.77, 1.47) 0.705
 Extremity Reference Reference
Tumor ulceration 0.88 (0.54, 1.43) 0.594 1.20 (0.82, 1.75) 0.349
Microsatellites 0.84 (0.45, 1.56) 0.582 0.92 (0.54, 1.55) 0.746
AJCC 8th edition stage
 IIIA 0.70 (0.39, 1.26) 0.234 0.37 (0.23, 0.59) <0.001
 IIIB 0.57 (0.32, 1.02) 0.060 0.71 (0.47, 1.08) 0.108
 IIIC/D Reference Reference
Nodal tumor ≥1 millimeter 3.62 (2.33, 5.63) <0.001 1.65 (1.20, 2.27) 0.002
Extranodal tumor extension 1.70 (0.89, 3.24) 0.106 1.52 (0.84, 2.76) 0.165
a

Models contained random intercept to account for clustering of patients within facility