TABLE 1.
Baseline Characteristics of Patients With Thrombocytopenia at the Time of Continuous Kidney Replacement Therapy Initiation
| Characteristicsa | (n = 284) | TPE (n = 118) | No TPE (n = 166) | p |
|---|---|---|---|---|
| Age at ICU admission (mo) | 69 (13–168) | 81 (16–187) | 57 (9–158) | 0.05 |
| Sex (female) | 145 (51.1) | 63 (53.4) | 82 (49.4) | 0.51 |
| Body surface area (m2) | 0.78 (0.47–1.41) | 0.81 (0.50–1.66) | 0.74 (0.37–1.33) | 0.03 |
| Baseline serum creatinine (mg/dL) | 0.30 (0.13–0.60) | 0.30 (0.15–0.60) | 0.25 (0.08–0.50) | 0.05 |
| Chronic kidney disease | 22 (7.8) | 4 (3.4) | 18 (10.8) | 0.02 |
| PELOD-2 score at ICU admission | 6 (4–9) | 6 (3–10) | 6 (4–9) | 0.83 |
| PELOD-2 score at CKRT initiation | 10 (7–12) | 10 (8–12) | 9 (7–11) | < 0.001 |
| Platelet count at CKRT initiation (cell/mm3) | 64 (46–85) | 51 (33–72) | 48 (33–67) | 0.40 |
| Extracorporeal membrane oxygenation during ICU admission | 53 (18.7) | 27 (16.3) | 26 (22.0) | 0.22 |
| Methicillin-resistant Staphylococcus aureus during ICU admission | 32 (11.3) | 8 (6.8) | 24 (14.5) | 0.04 |
CKRT = continuous kidney replacement therapy, PELOD-2 = Pediatric Logistic Organ Dysfunction-2, TPE = therapeutic plasma exchange.
a
Data are expressed as median (interquartile range) or n (%).