Table 1.

Inclusion and exclusion criteria

PICO	Inclusion criteria	Exclusion criteria
Patients	Cancer patients (all entities and stages) Adult patients (age > 18) Guideline-based cancer treatment	Preclinical studies Study population with children or only precancerous conditions, if numeral details are not reported separately Primary prevention
Intervention	Every intervention containing homeopathy No restrictions regarding the type of homeopathy, dose, mode of application
Comparison	All possible control groups (active control, placebo, standard care, observation)
Outcome	Influence on toxicity of cancer treatment (skin reaction, nausea and vomiting, joint pain and stiffness, oral mucositis) Time to drain removal Survival Menopausal symptoms Quality of life and other psychological outcomes Sleep Safety and side effects	No patient centred outcomes (e.g. laboratory parameters)
Others	All study types (including SRs, RCTs, CTs, one-armed studies and retrospective studies) Language: German and English Full publication	Other publication type than primary investigation/report Case reports Gray literature (conference articles, abstracts, comments, letters, ongoing studies, unpublished literature, etc.) Full text not available in German or English