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. 2023 Feb 17;37(2):153–166. doi: 10.1007/s40290-023-00462-2
The 50 identified studies reporting clinical information about complications of drug-induced hyperprolactinaemia applied varying thresholds of prolactin levels to diagnose the condition. Future research should apply accepted consensus on elevated prolactin levels to allow better comparison across studies and likely more consistent results.
Most of the symptoms reported were menstrual cycle bleeding disorders, breast or lactation disorders, and sexual dysfunction. Patients presenting with these complications were receiving antipsychotics, prokinetic drugs, and antidepressants.
Limited clinical information exists about the complications of hyperprolactinaemia induced by drugs, especially in the long term, so additional research is needed to understand these adverse effects.