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. 2022 Jul 16;149(5):1929–1939. doi: 10.1007/s00432-022-04183-y

Table 4.

Observed second-line treatments in the follow-up period

Frequency of observed treatments in the second LOT following platinum-based therapy based on 79 patients analyzed, N (%)
Observed agents/procedures
 Paclitaxel 16 (20.3%)
 Carboplatin 16 (20.3%)
 Medroxyprogesteronea 10 (12.7%)
 Doxorubicina,b 8 (10.1%)
 Gemcitabine 7 (8.9%)
 Tamoxifen 6 (7.6%)
 Megestrola 6 (7.6%)
 Trabectedin 6 (7.6%)
 22 other agents/procedures (< 6 patients) 36 (45.6%)
Observed regimen
 Medroxyprogesterone (monotherapy) 7 (8.9%)
 Carboplatin and paclitaxel 6 (7.6%)
 Doxorubicin (monotherapy)b 6 (7.6%)
 42 other combinations (< 6 patients) 60 (75.9%)

EC endometrial cancer, LOT line of treatment

aApproved for the EC indication in Germany; bDoxorubicin and liposomal doxorubicin data were captured separately but were not distinguished between in these analyses