Table 1.
Follow-up time for the detection of lung tumors in patients with ESCC
| References | Total LSPTs, n | History of LC, n (%) | Synchronous LSPTs, n (%) | Metachronous LSPTs, n (%) | Time from LC in history to ESCC | Time to detection of metachronous LSPTs |
|---|---|---|---|---|---|---|
| Ven et al. (2020) | 219 | – | 123 (56.2) | 96 (43.8) | – | Median 3.2 year (IQR 1.9–4.5) |
| Yoshida et al. (2020) | 22 | 4 (18.2) | 2 (9.1) | 16 (72.7) | NR | NR |
| Yamaguchi et al. (2018) | 5 | – | – | 5 (100.0) | – | NR |
| Otowa et al. (2016) | 6 | 4 (66.7) | 2 (33.3) | 0 | NR | – |
| Lee et al. (2013) | 18 | 1 (5.6) | 9 (50.0) | 8 (44.4) | NR | NR |
| Chuang et al. (2008) | 338 | 226 (66.9) | 30 (26.8) | 82 (73.2) |
< 12 months n = 62 1–4 year n = 83 5–9 year n = 48 ≥ 10 year n = 33 |
6–11 months n = 6 1–4 year n = 43 ≥ 5 year n = 33 |
| Motoyama et al. (2003) | 9 | – | – | 9 (100.0) | – | Reported for 5 patients: 12, 14, 20, 23, 43 and 112 months |
| Kokawa et al. (2001) | 13 | 2 (15.4) | 4 (30.8) | 7 (53.8) | NR | Mean 23 months (sd 10.4) |
| Kumagai et al. (2001) | 5 | 1 (20.0) | 3 (60.0) | 1 (20.0) | NR | NR |
| Ribeiro Júnior et al. (1999) | 2 | 1 (50.0) | 0 | 1 (50.0) | 2 years | 6 year |
| Poon et al. (1998) | 8 | 4 (50.0) | 2 (25.0) | 2 (25.0) | NR | NR |
| Voormolen et al. (1995) | 3 | 1 (33.3) | 1 (33.3) | 1 (33.3) | NR | NR |
| Fekete et al. (1994) | 39 | 7 (17.9) | 22 (56.4) | 10 (25.6) | Mean 46 months (range 18–77)a | |
| Fogel et al. (1985) | 2 | 1 (50.0) | 0 | 1 (50.0) | 84 months | 21 months |
| Total | 675 | 252 | 198 | 239 | ||
ESCC esophageal squamous cell carcinoma, IQR interquartile range, LC lung cancer, LSPT lung second primary tumor, NR not reported, sd standard deviation
aTime interval between the diagnosis of ESCC and the diagnosis of LC