Table 1.
Patient characteristics, biopsy techniques, histology, PD-L1 expression and neoadjuvant therapeutic regimen
Study cohort | |
---|---|
Patient characteristics | n = 113 |
Male (%, n) | 60% (71) |
Age | 65 ± 9 |
Biopsy techniques | n = 146 |
Brush cytology (%, n) | 21.2% (31) |
Endobronchial biopsy (%, n) | 19.9% (29) |
EBUS-TBNA (%, n) | 8.2% (12) |
TBFB (%, n) | 22.6% (33) |
CT-guided biopsy (%, n) | 28.1% (41) |
Histology derived from biopsy | n = 114 |
Adenocarcinoma (%, n) | 60.5% (69) |
Squamous cell carcinoma (%, n) | 31.6% (36) |
Adenosquamous carcinoma (%, n) | 3.5% (4) |
Large cell/neuroendocrine carcinoma (%, n) | 0.9% (1) |
Carcinoid | 0.9% (1) |
NSCLC NOS | 2.6% (3) |
PD-L1 expression on tumour cells derived from biopsies specimens | n = 114 |
Δ TPS (%) | 27.9 ± 32.6% |
TPS ≥ 50% (%, n) | 68.4% (78) |
TPS < 50% (%, n) | 31.6% (36) |
Neoadjuvant therapeutic regimen | n = 27 |
Chemotherapy alone | 74.1% (20) |
Chemotherapy and immunotherapy | 14.8% (4) |
Chemotherapy and radiation therapy | 11.1% (3) |