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. 2023 Mar 30;14:1151335. doi: 10.3389/fimmu.2023.1151335

Table 2.

Universal health coverage of different therapies for patients with Primary Immunodeficiencies (PID).

Types of coverage Reimbursement level, N=6 (%)
Not applicable a Paid fully by patient or patient’s family Up to 50% From 51 to 69% From 70 to 90% From 91 to 100%
A) Biological treatment
 Enzymes 5 (83.3) 1 (16.7) 0 0 0 0
 Immunosuppressors 2 (33.3) 2 (33.3) 1 (16.7) 0 1 (16.7) 0
 Monoclonal antibodies 1 (16.7) 3 (50.0) 2 (33.3) 0 0 0
 Cytokines 2(33.3) 3 (50.0) 1 (16.7) 0 0 0
 Growth Factor 1 (16.7) 1 (16.7) 1 (16.7) 0 2 (33.3) 1 (16.7)
 C1 inhibitor 5 (83.3) 1 (16.7) 0 0 0 0
 Thrombopoietin 3 (50.0) 2 (33.3) 0 0 1 (16.7) 0
B) Routes of immunoglobulin
 IVIG - b 2 (33.3) 0 0 4 (66.7) 0
 SCIG - b 3 (50.0) 1 (16.7) 0 1 (16.7) 0
 FSCIG 4 (66.7) 0 2 (33.3) 0 0 0
C) Anti-infectious
 Antibiotics - b 2 (33.3) 0 0 3 (50.0) 1 (16.7)
 Antivirals - b 2 (33.3) 0 0 3 (50.0) 1 (16.7)
 Antifungals - b 2 (33.3) 0 0 3 (50.0) 1 (16.7)
 Antiparasitic - b 2 (33.3) 0 0 2 (33.3) 2 (33.3)
D) Vaccines 1 (16.7) 2 (33.3) 0 1 (16.7) 1 (16.7) 1 (16.7)
E) Curative treatments
 Bone marrow transplant 2 (33.3) 1 (16.7) 1 (16.7) 1 (16.7) 1 (16.7) 0
F) Diagnosis testing
 Biological 2 (33.3) 2 (33.3) 2 (33.3) 0 2 (33.3) 0
 Genetic 2 (33.3) 3 (50.0) 2 (33.3) 0 0 0
 Prenatal 3 (50.0) 2 (33.3) 2 (33.3) 0 0 0
a

Indicates that the treatment options were not available in the country, hence had no data on the coverage level.

b

not determined.

Descriptive analysis was used to compare the coverage level of different PID treatment options in 6 SEA countries. We stratified the coverage level into five different groups and the results were expressed in n (%), where n represented the number of countries.