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. 2023 Mar 30;14:1170166. doi: 10.3389/fimmu.2023.1170166

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Copyright © 2023 Wang, Peng and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Metabolomic profiling of identified metabolites. (A) Survival of mice immunized by live E. tarda vaccine and then challenged by EIB202. (B) Representative total ion current chromatogram from control and live groups. (C) Reproducibility of metabolomic profiling platform. The correlation coeffcient is shown by two technical replicates of metabolite abundances. (D) Category of the identified metabolites. (E) Cluster analysis of metabolites. Heat map shows differential metabolites. Green and red color indicates decrease and increase of metabolites, respectively (see color scale).