TABLE 4.
Matches between significantly changed miRs and target proteins in exosomes after EPS.
| microRNA IDs | Confidence | Gene names | Protein names | Fold change |
|---|---|---|---|---|
| miR-1233-5p | High (predicted) | GANAB | Neutral alpha-glucosidase AB | 3.10 |
| miR-1233-5p | High (predicted) | S100A7 | Protein S100-A7 | −2.49 |
| miR-1233-5p | Moderate (predicted) | CLSTN1 | Calsyntenin-1 | −1.14 |
| miR-1233-5p | Moderate (predicted) | COL6A1 | Collagen alpha-1(VI) chain | −1.14 |
| miR-1233-5p | Moderate (predicted) | VCL | Vinculin | 1.26 |
| miR-1233-5p | Moderate (predicted) | PVR | PVR Cell Adhesion Molecule | −1.45 |
| miR-1233-5p | Moderate (predicted) | SYNPO2 | Synaptopodin-2 | 2.13 |
| miR-320b | High (predicted) | TFRC | Transferrin receptor protein 1 | 1.97 |
| miR-320b | Moderate (predicted) | WARS | Tryptophan-tRNA ligase | 2.01 |
| miR-4532 | Moderate (predicted) | CLSTN1 | Calsyntenin-1 | −1.14 |
| miR-4532 | Moderate (predicted) | PLEC | Plectin | 1.26 |
| miR-4532 | Moderate (predicted) | EEF2 | Eukaryoticelongation factor2 | 1.30 |
| miR-4532 | Moderate (predicted) | SEMA7A | Semaphorin 7A | −1.41 |
| miR-4532 | Moderate (predicted) | MAP4 | Microtubule-associated protein 4 | 1.73 |
| miR-4532 | Moderate (predicted) | RPS15A | 40S ribosomal protein S15a | 1.67 |
| miR-92b-5p | Moderate (predicted) | CLSTN1 | Calsyntenin-1 | −1.14 |
| miR-92b-5p | Moderate (predicted) | VCL | Vinculin | 1.26 |
| miR-92b-5p | Moderate (predicted) | SND1 | Staphylococcal nuclease domain-containing protein 1 | 1.63 |
| miR-4649-5p | High (predicted) | ZYX | Zyxin | 2.09 |
| miR-4433b-3p | High (predicted) | TFRC | Transferrin receptor protein 1 | 1.97 |
| miR-4433b-3p | Moderate (predicted) | COL6A1 | Collagen alpha-1(VI) chain | −1.14 |
| miR-4433b-3p | Moderate (predicted) | CNDP2 | Cytosolic non-specific dipeptidase | 1.96 |
| miR-1909-3p | High (predicted) | MAP1A | Microtubule AssociatedProtein1A | 1.28 |
| miR-1909-3p | High (predicted) | RNH1 | Ribonuclease inhibitor | 1.89 |
| miR-1909-3p | Moderate (predicted) | SERPING1 | Plasma protease C1 inhibitor | −1.22 |
| miR-1909-3p | Moderate (predicted) | CSF1 | Macrophage colony-stimulating factor 1 | −1.22 |
| miR-1909-3p | Moderate (predicted) | DES | Desmin | 1.28 |
| miR-1909-3p | Moderate (predicted) | GSN | Gelsolin | 1.31 |
| miR-1909-3p | Moderate (predicted) | BMP1 | Bone morphogenetic protein 1 | −1.52 |
| miR-1909-3p | Moderate (predicted) | FAM129B | Niban-like protein 1 | 1.95 |
| miR-1909-3p | Moderate (predicted) | TFRC | Transferrin receptor protein 1 | 1.97 |
| miR-2277-5p | High (predicted) | APOE | Apolipoprotein E | −1.54 |
| miR-2277-5p | Moderate (predicted) | SDF4 | 45 kDa calcium-binding protein/Stromal cell-derived factor 4 | −1.25 |
| miR-2277-5p | Moderate (predicted) | ZYX | Zyxin | 2.09 |
| miR-6749-5p | Moderate (predicted) | CLSTN1 | Calsyntenin-1 | −1.14 |
| miR-6749-5P | Moderate (predicted) | PVR | PVR Cell Adhesion Molecule | −1.45 |
| miR-6805-5p | High (predicted) | MAP4 | Microtubule-associated protein 4 | 1.73 |
| miR-6805-5p | Moderate (predicted) | COL6A1 | Collagen alpha-1(VI) chain | −1.14 |
| miR-6805-5p | Moderate (predicted) | CSF1 | Macrophage colony-stimulating factor 1 | −1.22 |
| miR-6805-5p | Moderate (predicted) | WARS | Tryptophan--tRNA ligase | 2.01 |
| miR-6805-5p | Moderate (predicted) | GANAB | Neutral alpha-glucosidase AB | 3.10 |
| miR-6735-5p | Moderate (predicted) | PLOD3 | Procollagen glycosyltransferase | 1.13 |
| miR-6735-5p | Moderate (predicted) | CSF1 | Macrophage colony-stimulating factor 1 | −1.22 |
| miR-6735-5p | Moderate (predicted) | VCL | Vinculin | 1.26 |
| miR-6735-5p | Moderate (predicted) | BMP1 | Bone morphogenetic protein 1 | −1.52 |
| miR-6735-5p | Moderate (predicted) | ITGBL1 | Integrin beta-like protein 1 | −1.64 |
| miR-6735-5p | Moderate (predicted) | RPS15A | 40S ribosomal protein S15a | 1.67 |
| miR-6735-5p | Moderate (predicted) | MAP4 | Microtubule-associated protein 4 | 1.73 |
| miR-6735-5p | Moderate (predicted) | AARS | Alanine--tRNA ligase, cytoplasmic | 2.00 |