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. 2023 Mar 30;17:1148292. doi: 10.3389/fnbeh.2023.1148292

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Copyright © 2023 Ronan, Korzan, Johnson, Lowry, Renner and Summers.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Serotonin sampling and neuronal origin in the CeA. (A) Representative schematic of microdialysis probe tip placement within the central nucleus of the amygdala (Paxinos and Watson, 1998). (B) Serotonin (5-HT) release (mean ± SEM; N = 4 rats) in the CeA over time. Values for –40, –20, and 0 min were used to normalize the data; presented as percent of baseline. Tetrodotoxin (TTX) perfused though the microdialysis probe significantly attenuates serotonin (5-HT) release in the CeA compared with samples taken prior to TTX treatment (–40, –20, 0 min; GLM-RMANOVA; p < 0.05).