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. 2023 Mar 30;14:1164278. doi: 10.3389/fimmu.2023.1164278

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Copyright © 2023 Xing, Lv, Zhu, Cong, Bian, Zhang, Gu, Chen, Tan, Su and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analysis of the influence and pathways of Gelsevirine in the ischemia penumbra zone by RNA-seq. (A) Different expressed genes were showed by volcano and (B) the clustering analysis was showed by heatmap. (C, D) GO and KEGG enrichment were used to evaluate the influence of Gelsevirine on stroke. (E, F) GSEA method was used to GO and KEGG enrichment analysis which can explore the effect of Gelsevirine on stroke. (G) Important pathways related to inflammatory changes by GSEA analysis.