Table 2.

Bone mineral density (BMD) and laboratory markers of the study group (n = 21)

Bone parameters	Baseline data		End of study		Absolute change V1-V6	P value
	Mean	± SD	Mean	± SD
DXA-Hip
Total hip BMD, g/cm²	0.76	0.09	0.80	0.08	0.04	0.0006
Total hip T-Score	−1.79	0.78	−1.53	0.76	0.26	0.0032
Femoral neck BMD, g/cm²	0.72	0.09	0.74	0.07	0.02	0.15
Femoral neck T-Score	−1.81	0.72	−1.68	0.70	0.13	0.021
DXA-Lumbar spine
Lumbar spine BMD, g/cm²	0.81	0.11	0.89	0.12	0.08	0.0017
Lumbar spine (L1-L4) T-score	−2.80	0.67	−1.83	1.36	0.97	0.011
Laboratory serum markers					Relative change V1-V6%
Calcium (mmol/L)	2.35	0.10	2.30	0.11	2.15	0.028
Phosphate (mmol/L)	1.07	0.11	1.02	0.16	4.43	0.18
Parathyroid hormone (mg/mL)	67.1	22.8	90.2	30.6	34.4	0.075
CTX (ng/mL)	0.42	0.24	0.15	0.15	64.1	<0.0001
Vitamin D (ng/mL)	37.0	12.9	41.5	11.8	12.2	0.11
P1NP (µg/L)	57.8	31.6	17.7	8.49	69.3	<0.0001