Table 3.

Spearman correlation assessing the association between the percentage of change in BMD and BTMs and the percentage of change in miRNA levels (V1 vs V6, N = 20)

miRNAs	Total hip BMD		Mean spine BMD		CTX		PINP
	Correlation value	FDR	Correlation value	FDR	Correlation value	FDR	Correlation value	FDR
miR-101-3p	0.107	0.295	0.025	0.865	−0 .446	<0 .0001	−0 .360	0 .005
miR-191-5p	0.266	0.088	0.134	0.596	−0 .399	<0 .0001	−0 .316	0 .013
miR-26b-5p	0.311	0.057	0.181	0.514	−0 .615	<0 .0001	−0 .465	0 .002
miR-32-5p	0.202	0.156	0.159	0.533	−0 .239	0 .003	−0.045	0.307
miR-4508	0.132	0.259	0.074	0.747	−0 .349	<0 .0001	−0.177	0.087
miR-454-3p	0 .536	0 .001	0 .402	0 .051	−0 .665	<0 .0001	−0 .434	0 .002
miR-584-5p	0 .490	0 .003	0 .499	0 .022	−0 .477	<0 .0001	−0 .362	0 .005
miR-126-3p	0 .639	<0 .0001	0 .423	0 .051	−0 .456	<0 .0001	−0 .257	0 .029
miR-140-5p	0 .338	0 .042	0.124	0.604	−0 .351	<0 .0001	−0 .407	0 .003
miR-142-3p	0 .584	<0 .0001	0 .395	0 .051	−0 .495	<0 .0001	−0 .288	0 .019
miR-181c-5p	−0.158	0.221	−0.041	0.854	−0 .295	0 .001	−0 .366	0 .005
miR-199a-5p	0 .610	<0 .0001	0 .401	0 .051	−0 .296	0 .001	−0 .286	0 .019
miR-26a-5p	0 .644	<0 .0001	0 .401	0 .051	−0 .582	<0 .0001	−0 .413	0 .003
miR-324-5p	0 .495	0 .003	0.369	0.069	−0 .443	<0 .0001	−0 .245	0 .033
miR-330-3p	0.293	0.067	0.096	0.689	−0 .323	0 .001	−0.138	0.137
miR-340-3p	0 .502	0 .002	0.288	0.177	−0 .269	0 .002	−0.127	0.148
miR-548c-5p	0.258	0.091	0.157	0.533	−0 .356	<0 .0001	−0 .276	0 .021
miR-744-5p	0 .539	0 .001	0.292	0.177	−0 .476	<0 .0001	−0 .288	0 .019
miR-1307-3p	0 .728	<0 .0001	0 .556	0 .010	−0 .561	<0 .0001	−0 .365	0 .005
miR-15a-5p	0.075	0.349	0.019	0.865	−0 .289	0 .001	−0 .223	0 .046

Bold data indicates that the correlations are significant (FDR < 0.05).