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. Author manuscript; available in PMC: 2023 Dec 1.
Published in final edited form as: Oral Oncol. 2022 Oct 28;135:106226. doi: 10.1016/j.oraloncology.2022.106226

TABLE 2.

Univariable and multivariable Cox proportional hazards models for associations between combinations of CD103+ TILs and PD-L1 CPS and survival outcomes. “Discordant” refers to CD103+ TILs high, PD-L1 CPS low and CD103+ TILs low, PD-L1 CPS high tumors. HR = hazard ratio.

OS DSS DFS
HR (95% CI) p-value HR (95% CI) p-value HR (95% CI) p-value
Univariable Models
CD103+ TILs high 0.54 (0.28, 1.02) 0.06 0.35 (0.15, 0.82) 0.03 0.44 (0.20, 0.94) 0.03
PD-L1 CPS high 0.61 (0.28, 1.34) 0.22 0.48 (0.16, 1.41) 0.18 0.70 (0.28, 1.74) 0.44
Multivariable Models
Discordant vs. Both Low 0.49 (0.24, 0.99) 0.05 0.31 (0.12, 0.80) 0.02 0.52 (0.23, 1.20) 0.52
Both High vs. Both Low 0.45 (0.18, 1.12) 0.09 0.29 (0.08, 1.03) 0.05 0.40 (0.13, 1.23) 0.11
Discordant and Both High vs. Both Low 0.48 (0.25, 0.90) 0.02 0.30 (0.13, 0.70) 0.005 0.48 (0.22, 1.02) 0.06