Table 1.
Baseline Characteristics for Study Participants (Analysis Set)
| Characteristics | CD Cohort | LTCF Cohort |
|---|---|---|
| Season 1 | ||
| N | 1251 | 664 |
| Age at enrollment, mean ± SD (years) | 65.1 ± 8.8 | 82.7 ± 8.5 |
| Age Group at Enrollment (Years) | ||
| 50–59 | 382 (30.5%) | |
| 60–64 | 238 (19.0%) | |
| 65–69 | 242 (19.3%) | 59 (8.9%) |
| 70–79 | 315 (25.2%) | 172 (25.9%) |
| ≥ 80 | 74 (5.9%) | 433 (65.2%) |
| Female sex, n (%) | 766 (61.2%) | 430 (64.8%) |
| Race, n (%) | ||
| White-Caucasian/European heritage | 1245 (99.5%) | 629 (94.7%) |
| Other | 6 (0.5%) | 35 (5.3%) |
| Educational Status, n (%) | ||
| None | 2 (0.2%) | 14 (2.1%) |
| Elementary | 307 (24.6%) | 177 (26.7%) |
| High School | 340 (27.2%) | 228 (34.3%) |
| Vocational/Technical | 291 (23.3%) | 67 (10.1%) |
| College/University | 309 (24.7%) | 178 (26.8%) |
| Missing | 2 (0.1%) | 0 (0.0%) |
| Smoking Status, n (%) | ||
| Current smoker | 210 (16.8%) | 48 (7.2%) |
| Former smoker | 406 (32.5%) | 200 (30.1%) |
| Never smoked | 635 (50.8%) | 416 (62.7%) |
| Frailty Status* | ||
| Fit | 909 (72.7%) | 39 (5.9%) |
| Prefrail | 232 (18.5%) | 79 (11.9%) |
| Frail | 105 (8.4%) | 419 (63.1%) |
| Missing | 5 (0.4%) | 127 (19.1%) |
| Any past or current relevant medical conditions, n (%) | 1167 (93.3%) | 660 (99.4%) |
| Any Current Medical Conditions, n (%) | 1139 (91.0%) | 659 (99.2%) |
| Vascular disorders | 689 (55.1%) | 530 (79.8%) |
| Metabolism and nutrition disorders | 545 (43.6%) | 388 (58.4%) |
| Diabetes | 192 (15.3%) | 176 (26.5%) |
| Obesity | 71 (5.7%) | 20 (3.0%) |
| Respiratory, thoracic, and mediastinal disorders | 249 (19.9%) | 170 (25.6%) |
| Chronic obstructive pulmonary disease | 67 (5.4%) | 92 (13.9%) |
| Asthma | 83 (6.6%) | 35 (5.3%) |
| Cardiac disorders | 189 (15.1%) | 287 (43.2%) |
| Left ventricular failure | 4 (0.3%) | 1 (0.2%) |
| Coronary artery disease | 21 (1.7%) | 25 (3.8%) |
| Renal and urinary disorders | 112 (9.0%) | 181 (27.3%) |
| Neoplasms benign, malignant, and unspecified (including cysts and polyps) | 68 (5.4%) | 45 (6.8%) |
| Hepatobiliary disorders | 47 (3.8%) | 15 (2.3%) |
| Received Any Influenza/Pneumococcal/Pertussis Vaccination, n (%) | 796 (63.6%) | 496 (74.7%) |
| Influenza vaccination | 711 (56.8%) | 480 (72.3%) |
| Pneumococcal vaccination | 247 (19.7%) | 208 (31.3%) |
| Pertussis vaccination | 177 (14.1%) | 21 (3.2%) |
| Season 2 | ||
| N | 1223 | 494 |
| Age at enrollment, mean ± SD (years) | 66.5 ± 8.8 | 83.4 ± 8.4 |
| Age Group at Enrollment (Years) | ||
| 50–59 | 294 (24%) | |
| 60–64 | 233 (19.1%) | |
| 65–69 | 255 (20.9%) | 34 (6.9%) |
| 70–79 | 345 (28.2%) | 126 (25.5%) |
| ≥80 | 96 (7.8%) | 334 (67.6%) |
| Female sex, n (%) | 749 (61.2%) | 318 (64.4%) |
| Race, n (%) | ||
| White-Caucasian/European heritage | 1218 (99.6%) | 464 (93.9%) |
| Other | 5 (0.4%) | 30 (6.1%) |
| Any past or current relevant medical conditions, n (%) | 1154 (94.4%) | 491 (99.4%) |
| Received Any Influenza/Pneumococcal/Pertussis Vaccination, n (%) | 838 (68.5%) | 410 (83.0%) |
| Influenza vaccination | 758 (62.0%) | 405 (82%) |
| Pneumococcal vaccination | 268 (21.9%) | 165 (33.4%) |
| Pertussis vaccination | 182 (14.9%) | 17 (3.4%) |
Abbreviations: CD, community-dwelling; LTCF, long-term care facility; N, number of participants in the analysis set; SD, standard deviation; n (%), number (percentage) of participants in a given category.
NOTE: Frailty status was determined based on the short physical performance battery total scores: fit 10–12 points; prefrail 8–9 points; frail ≤7 points.