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. 2023 Feb 1;6(1):59–77. doi: 10.20517/cdr.2022.90

Table 3.

Average IC50 value [nM] of the tested cancer and hybrid cell lines for compounds 1A-B, 2A-R, and 3, and SI (IC50 HDFa cells/IC50 tumor cell average)

2F 2C 2B 1A 2A 1B 2O 2R 3 2M 2P 2E 2J 2G, 2N, 2J, 2Q, 2K, 2D, 1C, 2H, 2L
Ø IC50 [nm] 43 47 49 52 53 53 203 227 321 330 330 374 396 > 500
SI 1163 1055 952 786 219 - - - - - - 59 - -