Table 3.
Average IC50 value [nM] of the tested cancer and hybrid cell lines for compounds 1A-B, 2A-R, and 3, and SI (IC50 HDFa cells/IC50 tumor cell average)
| 2F | 2C | 2B | 1A | 2A | 1B | 2O | 2R | 3 | 2M | 2P | 2E | 2J | 2G, 2N, 2J, 2Q, 2K, 2D, 1C, 2H, 2L | |
| Ø IC50 [nm] | 43 | 47 | 49 | 52 | 53 | 53 | 203 | 227 | 321 | 330 | 330 | 374 | 396 | > 500 |
| SI | 1163 | 1055 | 952 | 786 | 219 | - | - | - | - | - | - | 59 | - | - |