Table 4.
Characteristics of patients in low-level and high-level groups of systematic oxidative stress scores.
| Variables | Total (n = 955) | High-Level (n = 99) | Low-Level (n = 856) | p-Value |
|---|---|---|---|---|
| Gender | <0.001 | |||
| Male | 407 | 15 (15.2%) | 392 (45.8%) | |
| Female | 548 | 84 (84.8%) | 464 (54.2%) | |
| Age at surgery, years | 0.408 | |||
| ≤61 | 491 | 47 (47.5%) | 444 (51.9%) | |
| >61 | 464 | 52 (52.5%) | 412 (48.1%) | |
| Smoking history | 0.005 | |||
| No | 792 | 92 (92.9%) | 700 (81.8%) | |
| Yes | 163 | 7 (7.1%) | 156 (18.2%) | |
| Predominant pattern | 0.942 | |||
| Lepidic | 302 | 34 (34.3%) | 268 (31.3%) | |
| Acinar/Papillary | 562 | 56 (56.6%) | 506 (59.1%) | |
| Micropapillary/Solid | 59 | 6 (6.1%) | 53 (6.2%) | |
| Others | 32 | 3 (3.0%) | 29 (3.4%) | |
| Tumor size, cm | 0.012 | |||
| ≤1.0 | 72 | 3 (3.0%) | 69 (8.1%) | |
| 1.1–2.0 | 468 | 39 (39.4%) | 429 (50.1%) | |
| 2.1–3.0 | 316 | 41 (41.4%) | 275 (32.1%) | |
| 3.1–4.0 | 99 | 16 (16.2%) | 83 (9.7%) | |
| Visceral pleural invasion | 0.246 | |||
| Absent | 861 | 86 (86.9%) | 775 (90.5%) | |
| Present | 94 | 13 (13.1%) | 81 (9.5%) | |
| Lymphovascular invasion | 0.127 | |||
| Absent | 945 | 96 (97.0%) | 849 (99.2%) | |
| Present | 10 | 3 (3.0%) | 7 (0.8%) | |
| Spread through air space | 1 | |||
| Absent | 925 | 96 (97.0%) | 829 (96.8%) | |
| Present | 30 | 3 (3.0%) | 27 (3.2%) | |
| Epidermal growth factor receptor mutation | 0.806 | |||
| Without | 358 | 36 (36.4%) | 322 (37.6%) | |
| 19-del | 266 | 25 (25.2%) | 241 (28.2%) | |
| L858R | 279 | 33 (33.3%) | 246 (28.7%) | |
| Others | 52 | 5 (5.1%) | 47 (5.5%) | |
| Extent of surgery | 0.841 | |||
| Lobectomy | 863 | 89 (89.9%) | 774 (90.4%) | |
| Sub-lobectomy | 91 | 10 (10.1%) | 81 (9.5%) | |
| Adjuvant chemotherapy | 0.110 | |||
| No | 683 | 64 (64.6%) | 619 (72.3%) | |
| Yes | 272 | 35 (35.4%) | 237 (27.7%) |