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. 2023 Apr 13;21:146. doi: 10.1186/s12916-023-02854-2

Table 1.

The mean healthcare system costs per episode of respiratory syncytial virus (RSV)-associated mild and severe illness in children aged < 5 years, South Africa, 2014

Age group in months 0–2 3–5 6–8 9–11 12–59
Item Unit cost ($) Proportion of children tested or requiring treatment Duration of incurred cost (days) Mean cost per episode ($) Proportion of children requiring treatment Duration of incurred cost (days) Mean cost per episode ($) Proportion of children requiring treatment Duration of incurred cost (days) Mean cost per episode ($) Proportion of children requiring treatment Duration of incurred cost (days) Mean cost per episode ($) Proportion of children requiring treatment Duration of incurred cost (days) Mean cost per episode ($)
RSV-associated severe illness
 Facility fee (24H) 84.20 1.00 6.24 525.11 1.00 4.74 399.37 1.00 4.37 367.66 1.00 5.60 471.50 1.00 4.13 347.61
 Consultation (24H) 24.29 1.00 6.24 151.46 1.00 4.74 115.20 1.00 4.37 106.05 1.00 5.60 136.00 1.00 4.13 100.27
 ICU (24H) 691.61 0.03 7.00 165.41 0.01 3.83 25.80 0.02 0.67 10.97 0.02 0.67 8.55 0.04 2.00 51.48
 Chest X-ray 26.16 0.58 1.00 15.09 0.70 1.00 18.22 0.85 1.00 22.36 0.83 1.00 21.69 0.74 0.86 16.58
 Oxygen (24H) 34.29 0.45 1.20 18.44 0.44 1.20 18.23 0.44 1.20 18.23 0.53 1.20 21.84 0.91 1.03 32.06
 Antibiotic treatment 18.30 0.96 1.00 17.64 0.93 1.00 17.06 0.93 1.00 16.95 0.92 1.00 16.83 0.96 0.86 15.04
 Other medications 8.04 1.00 1.00 8.04 1.00 1.00 8.04 1.00 1.00 8.04 1.00 1.00 8.04 1.00 0.86 6.89
 HIV rapid 5.36 0.00 1.00 0.00 0.29 1.00 1.54 0.58 1.00 3.09 0.00 1.00 0.00 0.00 0.86 0.00
 HIV ELISA 4.38 0.15 1.00 0.64 0.25 1.00 1.08 0.04 1.00 0.19 0.07 1.00 0.32 0.24 0.86 0.90
 HIV PCR 30.54 0.28 1.00 8.43 0.23 1.00 7.02 0.44 1.00 13.58 0.48 1.00 14.76 0.31 0.86 8.03
 HIV viral load 27.23 0.00 1.00 0.11 0.01 1.00 0.27 0.00 1.00 0.00 0.02 1.00 0.50 0.05 0.86 1.28
 HIV CD4 +  14.55 0.00 1.00 0.03 0.01 1.00 0.09 0.00 1.00 0.00 0.00 1.00 0.00 0.04 0.86 0.47
 Bacterial culture 4.11 0.89 1.00 3.65 0.68 1.00 2.80 0.83 1.00 3.40 0.69 1.00 2.85 0.59 0.86 2.09
 Tuberculosis test 25.00 0.01 1.00 0.22 0.01 1.00 0.20 0.04 1.00 1.12 0.09 1.00 2.37 0.07 0.86 1.59
 Blood cell count 4.64 0.58 1.00 2.71 0.57 1.00 2.66 1.00 1.00 4.64 0.83 1.00 3.87 0.24 0.86 0.96
 CRP test 5.89 0.47 1.00 2.77 0.70 1.00 4.11 0.85 1.00 5.01 0.80 1.00 4.69 0.83 0.86 4.20
 ESR test 2.77 0.07 1.00 0.19 0.13 1.00 0.37 0.18 1.00 0.51 0.32 1.00 0.87 0.17 0.86 0.41
 Urea and creatinine 2.41 0.72 1.00 1.73 0.64 1.00 1.54 0.80 1.00 1.93 0.83 1.00 1.99 0.77 0.86 1.58
 Cost per episode 921.66 623.59 583.71 716.68 591.44
 Patient day equivalent (PDE) 147.70 131.56 133.57 127.98 143.26
RSV-associated mild illness
 Facility fee 8.4 1 1 8.4 1 1 8.4 1 1 8.4 1 8.4 1 1 8.4
 Consultation 8.9 1 1 8.9 1 1 8.9 1 1 8.9 1 8.9 1 1 8.9
 Antibiotic treatment 11.3 0.39 1 4.41 0.39 1 4.41 0.41 1 4.63 0. 42 1 4.75 0.45 1 5.09
 Other medication 3.3 0.99 1 3.27 0.99 1 3.27 0.99 1 3.27 0.99 1 3.27 0.99 1 3.27
 Total 24.98 24.98 25.20 1 25.29 25.66