Table 1.
Patient demographics and pre-ECMO characteristics of COVID-19 patients.
| Patient | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | All patients (n = 8) (%) |
|---|---|---|---|---|---|---|---|---|---|
| Age (years) | 22 | 38 | 35 | 33 | 31 | 29 | 29 | 34 | 30.9 ± 4.4 |
| Race | C | C | C | C | AA | H | C | C | C = 6 (75) AA = 1 (12.5) H = 1 (12.5) |
| BMI (kg/m2) | 35.8 | 49.2 | 34.2 | 37 | 40 | 32 | 33 | 32.2 | 35.7 ± 5.4 |
| Gestational age at time of delivery (weeks) | – | 25 | 29 | 26 | 27 | 32 | 32 | 37 | 29.7 ± 3.9 |
| COVID-19 symptoms onset (days) | 16 | 12 | 21 | 13 | 12 | 27 | 11 | 4 | 14.5 ± 6.5 |
| Days from symptoms onset to intubation | 16 | 6 | 19 | 9 | 6 | 20 | 8 | 4 | 11 ± 5.9 |
| Days from intubation to ECMO cannulation | 1 | 3 | 2 | 1 | 6 | 6 | 2 | 1 | 2.8 ± 2 |
| DM | N | Y | N | N | Y | N | Y | N | 3 (37.5%) |
| Gestational DM | – | – | N | N | Y | Y | Y | N | 3 (37.5%) |
| HTN | Y | N | N | N | Y | N | Y | N | 3 (37.5%) |
| WBCs (×103/μL) | 7.8 | 9.9 | 14.9 | 14.6 | 37.6 | – | 18 | 9.1 | 15.7 ± 8.5 |
| Platelets (×103/μL) | 286 | 303 | 193 | 218 | 276 | 106 | 294 | 225 | 212.7 ± 74.9 |
| ALT (unit/L) | 9 | 17 | 21 | 29 | 65 | 1012 | 14 | 12 | 123 ± 297 |
| AST (unit/L) | 27 | 29 | 42 | 32 | 77 | 169 | 20 | 17 | 46.9 ± 43.7 |
| Total Bilirubin (mg/dL) | 0.5 | 1.2 | 1.2 | 1.2 | 0.3 | – | 0.7 | 0.4 | 1 ± 0.6 |
| Creatinine (mg/dL) | 1.24 | 0.58 | 0.80 | 0.61 | 0.69 | 0.52 | 0.65 | 0.66 | 0.7 ± 0.2 |
| BUN (mg/dL) | 17 | 15 | 10 | 9 | 22 | – | 15 | 6 | 12 ± 5.2 |
| Lactate (mg/dL) | 0.85 | 1.12 | 0.81 | 1.33 | 1.7 | – | 1.53 | – | 1.1 ± 0.4 |
| Arterial pH | 7.32 | 7.42 | 7.29 | 7.41 | 7.35 | 7.21 | 7.4 | – | 7.4 ± 0.1 |
| CO2 (mmHg) | 59 | 40 | 45 | 34 | 33 | 63 | 49 | – | 47.2 ± 9.8 |
| P/F ratio | 63 | 72 | 84 | 68 | 47 | 124 | 76 | – | 74.4 ± 20 |
| PEEP | 12 | 15 | 12 | 15 | 14 | – | 8 | – | 12.7 ± 2.4 |
| HCO3 | 30 | 26 | 22 | 21 | 38 | – | 30 | – | 30 ± 6.3 |
| Oxygen saturation (%) | 88 | 94 | 95 | 94 | 79 | – | 95 | – | 91.6 ± 5.2 |
| SOFA | – | 9 | 9 | 11 | 9 | 9 | 8 | – | 9.4 ± 1 |
| Treatment received | |||||||||
| Convalescent plasma | N | Y | Y | N | N | N | N | N | 2 (25) |
| Antiviral | N | Y | Y | Y | Y | Y | N | N | 5 (62.5) |
| Antibiotics | Y | N | N | Y | Y | N | N | Y | 4 (50) |
| Glucocorticoids | N | Y | Y | Y | Y | Y | Y | N | 6 (75) |
ECMO: extracorporeal membrane oxygenation; COVID-19: coronavirus disease 2019; C: Caucasian; AA: African American; H: Hispanic; BMI: Body Mass Index; DM: diabetes mellitus; HTN: hypertension; WBC: white blood cells; ALT: alanine aminotransferase; AST: aspartate aminotransferase; BUN: blood urea nitrogen; PEEP: positive end-expiratory pressure; SOFA: sequential organ failure assessment; Y: yes; N: no; P/F: PaO2/FiO2-ratio; –: unknown or not measured.
The data are presented as mean ± SD or number (%).