Table 6.

Logistic regression analysis of frequency of homozygous haplotypes and the severity of liver disease

Haplotypea				Unadjusted				Adjustedb
				OR	95% CI		p	OR	95% CI		p
rs4238001	rs61932577	rs5888	n		Lower	Upper			Lower	Upper
G	C	C	38	0.58	0.27	1.25	0.16	0.64	0.21	2.02	0.45
	C	C	47	0.54	0.26	1.09	0.09	0.46	0.16	1.37	0.17
	C	T	54	2.26	1.22	4.16	0.009	2.81	1.06	7.46	0.038
G		C	51	0.60	0.30	1.18	0.14	0.74	0.29	1.86	0.52
G	C	T	40	2.20	1.10	4.35	0.024	2.37	0.78	7.20	0.13
G		T	42	1.96	1.00	3.82	0.049	1.91	0.65	5.60	0.24

Abbreviations: CI, confidence interval; n, number of subjects with homozygous haplotype; OD, odd ration.

^a Homozygous haplotype versus all other haplotypes present;

^b Adjusted for gender, age at biopsy, estimated duration of infection and alcohol.