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. 2022 Nov 25;95(1):e28322. doi: 10.1002/jmv.28322

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© 2022 The Authors. Journal of Medical Virology published by Wiley Periodicals LLC.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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The number and location of predicted G4‐forming sequences in monkeypox virus (MPXV) genomes. (A) A comparison between the predicted number of G4‐forming sequences in MPXV genomes obtained between 1958 and 2021 and the current 2022 outbreak. Individual points represent a single MPXV genome, and the columns represent the mean. The number (B) and (C) frequency of G4‐forming sequences per kbp located within annotated genomic features. Data in (B) and (C) represent the combined total of all genomes analyzed. Error bars represent the SD. Data is representative of 136 individual genomes collected between 1958 and 2022.